Antigenic structure of the E2 glycoprotein from transmissible gastroenteritis coronavirus
نویسندگان
چکیده
منابع مشابه
Localization of antigenic sites of the E2 glycoprotein of transmissible gastroenteritis coronavirus.
Four antigenic sites of the E2 glycoprotein of transmissible gastroenteritis virus were defined by competitive radioimmunoassays of monoclonal antibodies (MAbs). Here, we describe the localization of these sites by testing the antigenicity of protein fragments and prokaryotic expression products of E2 gene fragments, and by sequencing of MAb-resistant (mar) mutants. Partial proteolysis of purif...
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The complete nucleotide sequence of cloned cDNAs containing the E2 glycoprotein-encoding region of the genome of transmissible gastroenteritis virus (TGEV) has been determined. A single large translatable frame of 4.3 kb starting at 8.2 kb from the 3' end of the genome was identified. Its deduced amino acid sequence contains the characteristic features of a coronavirus peplomer protein: the pre...
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ژورنال
عنوان ژورنال: Virus Research
سال: 1988
ISSN: 0168-1702
DOI: 10.1016/0168-1702(88)90059-7